
科学进步、医疗发展与生活方式的改善使人类寿命不断延长,但寿命越长,罹患痴呆症的风险就越高。最近,科学家发现,美国痴呆症(表现为记忆力、思维能力、沟通能力及整体认知功能渐进性衰退)年新增病例预计将从2020年的51.4万例翻倍增长至2060年的100万例。
值得庆幸的是,我们仍能采取行动降低患病风险。《柳叶刀》(The Lancet)2024年发表的一份报告指出,通过解决14个风险因素,近半数老年痴呆症病例可预防或延迟发病。这些风险因素包括听力损伤、吸烟、肥胖、社交孤立及高血压等。《自然-医学》(Nature Medicine)近期发表的一项大规模研究证实,仅控制高血压一项即可将老痴呆风险降低15%。
研究团队在《柳叶刀》发表的报告中写道:“这些发现带来了希望。预防老年痴呆的可能性巨大,而且总的来说,理论上消除这14个风险因素可避免近半数痴呆症病例。”
以下是在任何年龄都需要警惕的14个风险因素。
• 高胆固醇
• 视力衰退
• 教育水平偏低
• 听力损伤
• 高血压
• 吸烟
• 肥胖
• 抑郁症
• 缺乏运动
• 糖尿病
• 酗酒
• 创伤性脑损伤
• 空气污染
• 社会孤立
14个风险因素应对指南
研究人员强调应尽早实施干预措施。但诸如保障优质教育等部分因素个人难以掌控,因此研究人员认为政策改革对降低老年痴呆症发病率至关重要。这种政策转变可能包括:增加绿地空间以鼓励人们进行体育锻炼、改善教育促进认知发展、加强吸烟危害宣传及公共场所控烟等。
研究团队建议采取以下措施:
• 持续参与益智活动保持思维活跃。
• 听力受损者使用助听器。
• 减少噪音暴露,以降低听力受损风险。
• 在接触性运动中及骑行时戴头盔和头部保护装置以防止创伤性脑损伤。
• 定期锻炼——经常进行体育锻炼者罹患老年痴呆的可能性较小。
• 减少或彻底戒除吸烟。
• 预防或降低高血压,40岁后维持收缩压不超过130。
• 控制胆固醇水平,努力降低低密度脂蛋白(有害)胆固醇。
• 保持健康体重,尽早治疗肥胖,这也有助于预防糖尿病。
• 减少酒精摄入。
• 参与社区活动,或与他人同住以缓解社交孤立。
• 定期检查视力,及时治疗视力衰退。
• 了解空气污染暴露情况,并尽可能减少接触污染。
• 寻求帮助,治疗抑郁症。(财富中文网)
译者:刘进龙
审校:汪皓
科学进步、医疗发展与生活方式的改善使人类寿命不断延长,但寿命越长,罹患痴呆症的风险就越高。最近,科学家发现,美国痴呆症(表现为记忆力、思维能力、沟通能力及整体认知功能渐进性衰退)年新增病例预计将从2020年的51.4万例翻倍增长至2060年的100万例。
值得庆幸的是,我们仍能采取行动降低患病风险。《柳叶刀》(The Lancet)2024年发表的一份报告指出,通过解决14个风险因素,近半数老年痴呆症病例可预防或延迟发病。这些风险因素包括听力损伤、吸烟、肥胖、社交孤立及高血压等。《自然-医学》(Nature Medicine)近期发表的一项大规模研究证实,仅控制高血压一项即可将老痴呆风险降低15%。
研究团队在《柳叶刀》发表的报告中写道:“这些发现带来了希望。预防老年痴呆的可能性巨大,而且总的来说,理论上消除这14个风险因素可避免近半数痴呆症病例。”
以下是在任何年龄都需要警惕的14个风险因素。
• 高胆固醇
• 视力衰退
• 教育水平偏低
• 听力损伤
• 高血压
• 吸烟
• 肥胖
• 抑郁症
• 缺乏运动
• 糖尿病
• 酗酒
• 创伤性脑损伤
• 空气污染
• 社会孤立
14个风险因素应对指南
研究人员强调应尽早实施干预措施。但诸如保障优质教育等部分因素个人难以掌控,因此研究人员认为政策改革对降低老年痴呆症发病率至关重要。这种政策转变可能包括:增加绿地空间以鼓励人们进行体育锻炼、改善教育促进认知发展、加强吸烟危害宣传及公共场所控烟等。
研究团队建议采取以下措施:
• 持续参与益智活动保持思维活跃。
• 听力受损者使用助听器。
• 减少噪音暴露,以降低听力受损风险。
• 在接触性运动中及骑行时戴头盔和头部保护装置以防止创伤性脑损伤。
• 定期锻炼——经常进行体育锻炼者罹患老年痴呆的可能性较小。
• 减少或彻底戒除吸烟。
• 预防或降低高血压,40岁后维持收缩压不超过130。
• 控制胆固醇水平,努力降低低密度脂蛋白(有害)胆固醇。
• 保持健康体重,尽早治疗肥胖,这也有助于预防糖尿病。
• 减少酒精摄入。
• 参与社区活动,或与他人同住以缓解社交孤立。
• 定期检查视力,及时治疗视力衰退。
• 了解空气污染暴露情况,并尽可能减少接触污染。
• 寻求帮助,治疗抑郁症。(财富中文网)
译者:刘进龙
审校:汪皓
Improvements in science, medicine, and lifestyle factors have allowed people to live longer than ever—but the longer you live, the more your risk of dementia increases. Recently, scientists discovered that the number of Americans who will develop dementia—a progressive decline in memory, thinking skills, communication, and overall cognitive ability—is estimated to double from 514,000 new cases each year in 2020 to one million cases each year by 2060.
Thankfully, there are steps you can take to lower your risk of developing dementia. As a 2024 report published in The Lancet found, nearly half of dementia cases could be prevented or delayed by addressing 14 risk factors—including hearing impairment, smoking, obesity, social isolation, and high blood pressure. A massive new study published in Nature Medicine found that even just addressing high blood pressure could reduce your risk of dementia by 15%.
“These findings provide hope,” the authors wrote in The Lancet. “The potential for prevention is high and, overall, nearly half of dementias could theoretically be prevented by eliminating these 14 risk factors.”
Here are the 14 risk factors you should be paying attention to—at any age.
• High cholesterol
• Vision loss
• Lower levels of education
• Hearing impairment
• High blood pressure
• Smoking
• Obesity
• Depression
• Physical inactivity
• Diabetes
• Excessive alcohol consumption
• Traumatic brain injury
• Air pollution
• Social isolation
Tips to tackle all 14 risk factors
Researchers emphasize that interventions should happen as early in life as possible. But some, such as ensuring a good quality education, can be difficult to control on your own—which is why they say policy changes could be crucial to help decrease dementia cases. Such policy shifts could include providing more green space to encourage people to be physically active, or improving education to support cognitive development, or better educating people about the risks of smoking and limiting smoking in public spaces.
The authors also suggest taking these steps:
• Engage in cognitively stimulating activities throughout your life to maintain strong thinking and intellect.
• Use hearing aids if you suffer from hearing loss.
• Decrease harmful noise exposure to reduce hearing loss.
• Use helmets and head protection in contact sports and on bicycles to prevent traumatic brain injuries.
• Exercise regularly—those who engage in sports and workout frequently are less likely to develop dementia.
• Reduce cigarette smoking or stop entirely.
• Prevent or reduce high blood pressure and maintain systolic blood pressure of 130 or less after age 40.
• Stay on top of your cholesterol, and work to lower your LDL (bad) cholesterol.
• Maintain a healthy weight and treat obesity as early as possible—which can also help prevent diabetes.
• Reduce alcohol consumption.
• Participate in community activities or try to live with others to reduce social isolation.
• Get vision screenings and seek treatment for vision loss.
• Understand your exposure to air pollution and try to reduce where possible.
• Seek help to treat depression.